Letrozole is a medication primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. This aromatase inhibitor functions by lowering estrogen levels in the body, which can help to slow or reverse the growth of certain breast tumors.
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Key Effects of Letrozole
Letrozole has several key effects that contribute to its role in breast cancer treatment:
- Reduction of Estrogen Levels: By inhibiting aromatase, Letrozole significantly decreases the production of estrogen in the body.
- Slowing Tumor Growth: Lower estrogen levels can slow the proliferation of hormone-sensitive tumors, leading to better outcomes for patients.
- Post-Surgery Usage: Often prescribed after surgery to prevent recurrence of cancer, Letrozole can help minimize the risk of cancer returning.
- Bone Health Monitoring: As Letrozole can affect bone density, regular monitoring may be necessary to prevent osteoporosis.
Potential Side Effects
While Letrozole is effective, it is important to be aware of potential side effects, which include:
- Hot flashes
- Joint pain
- Fatigue
- Nausea
- Bone thinning or osteoporosis
Conclusion
Letrozole is a valuable therapy for postmenopausal women battling breast cancer. Its ability to lower estrogen levels plays a crucial role in managing hormone-sensitive breast cancer. However, patients should be informed about its side effects and maintain conversations with their healthcare providers to ensure optimal treatment outcomes.